It is rapidly and nearly completely absorbed (more than 90% bioavailable) when administered orally. Peak blood plasma concentrations are achieved in 1-3 hours after oral administration of 1, 5, and 25 mg/kg to dogs. It is approximately 8 hours (range 4.5-9.8 hours). It has a small volume of distribution and a low systemic clearance. It is highly bound to plasma protein.
It is metabolized in the liver by conjunction and oxidation. The excretion of the glycuronide conjugate is mainly fecal after biliary excretion. For faster pain relief in Osteoarthritis and other musculo-skeletal disorders, pre and post- orthopaedic surgery and Trauma
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