Enrofloxacin Tablet is indicated for use in dogs and cats in the treatment of bacterial infections of alimentary , respiratory and urogenital tracts, skin , secondary wound infections and otitis externa.Enrofloxacin is bactericidal in action with activity against Gram positive and Gram negative bacteria and mycoplasmas. The mechanism of action of the quinolones is unique among antimicrobials – they act primarily to inhibit bacterial DNA gyrase, an enzyme responsible for controlling the super coiling of bacterial DNA during replication. Resealing of the double standard helix is inhibited resulting in irreversible degradation of the chromosomal DNA.